In anime, sometimes when a character winks a star is drawn coming out of their eye. Why does this happen? I have absolutely no idea. What does it mean? It means it's a wink strong enough to make stars come out. Most likely, it's done just because it looks cute.
- winku de hoshi ga deru
A star leaves due to a wink.
A star comes out with a wink.
This has basically nothing to do with star eyes.
Anime: Lucky☆Star, らき☆すた (Episode 2)